Pixelorama
Pixelorama includes layers, frame animation, palettes, tile mode, onion skinning, and sprite-sheet export for common pixel-production workflows.
Why use it
Its MIT license and familiar pixel workflow make it a strong open alternative to Aseprite and allow teams to extend it themselves.
Where it fits
Use art, animation, audio, levels, and narrative to make the game easy to read and its world convincing.
What to check
Its ecosystem, plug-in count, and some advanced workflows trail Aseprite, so export settings should be validated in the target engine.